About Tunnel single-arm
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5 FAQs about [Tunnel single-arm]
What is a single-arm trial?
Single-arm trials refer to a design method in clinical research where only one experimental group is established, without the inclusion of a parallel control group. 9 It can be considered as an alternative when the design of an RCT is not feasible. The study design is open and does not involve randomisation or blinding.
How secure is tunnel?
Tunnel provides industry-best security and builds on TLS 1.3 libraries, implements SSL Pinning to ensure no MITM attacks, and includes client certificates on the allowlist to ensure identity integrity.
Are single-arm trials feasible?
Although randomised controlled trials are considered the gold standard in clinical research, they are not always feasible due to limitations in the study population, challenges in obtaining evidence, high costs and ethical considerations. As a result, single-arm trial designs have emerged as one of the methods to address these issues.
Why are single-arm trials better than randomised controlled trials?
Single-arm trials have certain ethical advantages over randomised controlled trials, such as providing equitable treatment, respecting patient preferences, addressing rare diseases and timely management of adverse events.
Do single-arm trials have a control group?
Balancing risks and benefits: Since single-arm trials inherently lack a control group for comparison, researchers must carefully assess and inform patients about the potential risks associated with the trial intervention, ensuring their full understanding.